Down syndrome is one of the most common genetic birth defects. Usually, children born with the condition have some degree of mental retardation, as well as characteristic physical features. Many of these children also have other health problems.

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Most people with Down syndrome have mild or moderate mental retardation. Mental retardation is a disability that limits a person’s intellectual abilities as well as the behaviors that people use to function in their everyday lives.

People with Down syndrome may also have delayed language development and slow motor development, which is the ability to use their muscles.

Some of the common physical signs of Down syndrome include:

• A flat face with an upward slant to the eye, a short neck and abnormally shaped ears.
• A deep crease in the palm of the hand.
• White spots on the iris of the eye.
• Poor muscle tone, loose ligaments.
• Small hands and feet.

Even though people with Down syndrome may have some physical and mental features in common, the symptoms of Down syndrome can range from mild to severe.

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